ComBEfive

Description

ComBEfive is a pentavalent combination vaccine containing Diphtheria toxoid, Tetanus toxoid, killed Bordetella pertussis bacilli whole cell, Hepatitis B surface antigen (rDNA) and Haemophilus influenzae Type B conjugate vaccine.

This combination vaccine is administered for active immunization against Diphtheria, Tetanus, Pertussis (whooping cough), Hepatitis B and Haemophilus influenzae type b infections (meningitis, septicaemia, cellulitis, arthritis, epiglottitis, etc)

Immunization guideline:

The recommended dose (0.5 ml) of the vaccine must be administered.

DTP-HepB-Hib vaccine can be given in a 3 dose schedule at 6, 10 and 14 weeks after the birth dose of Hep B vaccine. Pentavalent vaccines are not recommended for DTP Booster doses.

Additional information

manufacturer

Biological E Limited

country-of-manufacture

India

vaccine-type

Diphtheria-Tetanus-Pertussis (whole cell)-Hepatitis B-Haemophilus influenzae type b

pharmaceutical-form

Liquid, Lyophilized

package-size

1 Dose

route-of-administration

Intramuscular

preservative

Thiomersal

Contraindications

Known hypersensitivity to any component of the vaccine, or to subjects having shown signs of hypersensitivity after previous administration of diphtheria, tetanus, pertussis, hepatitis B or Hib vaccines. ComBEfive is contra-indicated if the child has experienced an encephalopathy of unknown nature, occurring within 7 days following previous vaccination with pertussis containing vaccine. In these circumstances the vaccination course should be continued with diphtheria, tetanus, Hib and hepatitis B vaccines