Adacel consists of Tetanus toxoid, reduced Diptheria toxoid and acellular Pertussis vaccine adsorbed. Adacel vaccine is indicated for active booster immunization for the prevention of Tetanus, Diphtheria, and Pertussis as a single dose in persons 11 through 64 years of age.
A single 0.5 ml dose of Adacel is given intramuscularly in the deltoid region of upper arm. 5 years should have passed since the last dose of any DTP vaccine administered to the person. Adacel may be given in the case of injury if no other vaccine containing Tetanus toxoid, Pertussis vaccine and Diptheria toxoid being given to the patient earlier.
The most common local and systemic adverse reactions to Adacel vaccine include injection site pain, erythema, and swelling; headache, body ache, tiredness, and fever. Other adverse reactions may occur.
A severe allergic reaction after a previous dose of Adacel vaccine or any other tetanus toxoid, diphtheria toxoid or pertussis containing vaccine, or to any component, or encephalopathy within 7 days of a previous dose of a pertussis containing vaccine, is a contraindication.